Journal Articles and Reviews:

[J33]  Rita Reig-Viader, Diego del Castillo-Berges, Albert Burgas-Pau, Daniel Arco-Alonso, David Ramos-Vicente, Carlos Sindreu and Àlex Bayés.
Synaptic proteome diversity is primarily driven by gene regulation of glutamate receptors and their regulatory proteins.
bioRxiv, 4th April 2024
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[J32] Juliana Ribeiro-Constante, Alba Tristán-Noguero,(…), Diego Del Castillo-Berges, Marc Schwartz-Palleja, Oscar Sans Capdevila, Angeles García-Cazorla, Àlex Bayés* and Itziar Alonso-Colmenero*. (* Corresponding authors).
Developmental outcome of electroencephalographic findings in SYNGAP1 encephalopathy.
Frontiers in Cell and Developmental Biology 2024 Mar 5:12:1321282
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[J31] Amparo Roig Adam et al. SynGO Consortium (Inc. Àlex Bayés)
Transcriptional diversity in specific synaptic gene sets discriminates cortical neuronal identity.
Biology Direct 2023 May 9;18(1):22.
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[J30] Trubetskoy V. et al. SynGO Consortium (Inc. Àlex Bayés)
Mapping genomic loci implicates genes and synaptic biology in schizophrenia.
Nature 2022 Apr;604(7906):502-508.
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[J29] Murat Kilinc, Vineet Arora, Thomas K. Creson, Camilo Rojas, Aliza A. Le, Julie Lauterborn, Brent Wilkinson, Nicolas Hartel, Nicholas Graham, Adrian Reich, Gemma Gou, Yoichi Araki, Àlex Bayés, Marcelo P. Coba, Gary Lynch, Courtney A. Miller, Gavin Rumbaugh.
Endogenous Syngap1 alpha splice forms promote cognitive function and seizure protection.
eLife 2022 Apr 8;11:e75707.
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[J28] Jeffrey C. Watkins, Richard H. Evans, Àlex Bayés, Sam A. Booker, Alasdair Gibb, Angela M. Mabb, Mark Mayer, Jack R. Mellor, Elek Molnáf, Li Niu, Arturo Ortega, Yuriy Pankratov, David Ramos-Vicente, Ada Rodríguez-Campuzano h, Antonio Rodríguez-Moreno, Lu-Yang Wang, Yu Tian Wang, Lonnie Wollmuth, David J. A. Wyllie, Min Zhuo, Bruno G. Frenguelli
21st century excitatory amino acid research: A Q & A with Jeff Watkins and Dick Evans.
Neuropharmacology 2021 Oct 15;198:108743.
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[J27] David Ramos-Vicente, Seth Gn Grant, Àlex Bayés
Metazoan evolution and diversity of glutamate receptors and their auxiliary subunits
Neuropharmacology 2021 Sep 1;195:108640. doi: 10.1016/j.neuropharm.2021.108640.
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[J26] Elena Cid, Angel Marquez-Galera, Manuel Valero, Beatriz Gal, Daniel C Medeiros, Carmen M Navarron, Luis Ballesteros-Esteban, Rita Reig-Viader, Aixa V Morales, Ivan Fernandez-Lamo, Daniel Gomez-Dominguez, Masaaki Sato, Yasunori Hayashi, Àlex Bayés, Angel Barco, Jose P Lopez-Atalaya, Liset M de la Prida
Sublayer- and cell-type-specific neurodegenerative transcriptional trajectories in hippocampal sclerosis
Cell Reports 2021 Jun 8;35(10):109229. doi: 10.1016/j.celrep.2021.109229
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[J25] Ana Cazurro-Gutiérrez, Anna Marcé-Grau, Marta Correa-Vela, Ainara Salazar, María I Vanegas, Alfons Macaya, Àlex Bayés, Belen Pérez-Dueñas.
ε-Sarcoglycan: Unraveling the Myoclonus-Dystonia Gene
Molecular Neurobiology 2021 Apr 22 doi: 10.1007/s12035-021-02391-0
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[J24] David Ramos-Vicente, Àlex Bayés.
AMPA Receptor Auxiliary Subunits Emerged During Early Vertebrate Evolution by Neo/Subfunctionalization of Unrelated Proteins
Open Biology 2020 Oct;10(10):200234. doi: 10.1098/rsob.200234
web; pdf; supplementary material

[J23] Gemma Gou, Adriana Roca-Fernandez, Murat Kilinc, Elena Serrano, Rita Reig-Viader, Yoichi Araki, Richard L. Huganir, Cristian de Quintana-Schmidt, Gavin Rumbaugh, Àlex Bayés.
SynGAP Splice Variants Display Heterogeneous Spatio-Temporal Expression And Subcellular Distribution In The Developing Mammalian Brain.
Journal of Neurochemistry 2020 Sep;154(6):618-634. doi: 10.1111/jnc.14988
web; pdf; supplementary information

[J22] David Soto, Mireia Olivella, Cristina Grau, Judith Armstrong, Clara Alcon, Xavier Gasull, Ana Santos-Gómez, Sílvia Locubiche, Macarena Gómez de Salazar, Roberto García-Díaz, Esther Gratacòs-Batlle, David Ramos-Vicente, Emeline Chu-Van, Benoit Colsch, Víctor Fernández-Dueñas, Francisco Ciruela, Àlex Bayés, Carlos Sindreu, Anna López-Sala, Àngels García-Cazorla, Xavier Altafaj.
L-serine dietary supplement is associated with clinical improvement of loss-of-function GRIN2B-related paediatric encephalopathy.
Science Signaling 2019 Vol. 12, Issue 586, eaaw0936.
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[J21] Frank Koopmans, Pim van Nierop Maria Andres-Alonso, Andrea Byrnes, Tony Cijsouw, Marcello P. Coba, L. Niels Cornelisse, Ryan J. Farrell, Hana L. Goldschmidt, Daniel P. Howrigan, Natasha K. Hussain, Cordelia Imig, Arthur P.H. de Jong, Hwajin Jung, Mahdokht Kohansalnodehi, Barbara Kramarz, Noa Lipstein, Ruth Lovering, Harold MacGillavry, Huaiyu Mi, Momchil Ninov, David Osumi-Sutherland, Rainer Pielot, Karl-Heinz Smalla, Haiming Tang, Katherine Tashman, Ruud F.G. Toonen, Chiara Verpelli, Rita Reig-Viader, Kyoko Watanabe, Jan van Weering, Tilmann Achsel, Ghazaleh Ashrafi, Nimra Asi, Tyler C. Brown, Pietro De Camilli, Marc Feuermann, Rebecca Foulger, Pascale Gaudet, Anouska Joglekar, Alexandros Kanellopoulos, Robert Malenka, Vittoria Mariano, Camila Pulido, Jaime de Juan Sanz, Morgan Sheng, Thomas C. Südhof, Hagen U. Tilgner, Claudia Bagni, Àlex Bayés, Thomas Biederer, Nils Brose, John Chua, Daniela C. Dieterich, Eckart D. Gundelfinger, Casper Hoogenraad, Richard L. Huganir, Reinhard Jahn, Pascal S. Kaeser, Eunjoon Kim, Michael R. Kreutz, Peter S. McPherson, Ben M. Neale, Vincent O’Connor, Danielle Posthuma, Timothy A. Ryan, Carlo Sala, Guoping Feng, Steven E. Hyman, Paul D. Thomas, August B. Smit, Matthijs Verhage.
SynGO: an evidence-based, expert-curated knowledgebase for the synapse.
Neuron 2019 May 22. pii: S0896-6273(19)30427-1.
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[J20]  Lleó A, Núñez-Llaves R, Alcolea D, Chiva C, Balateu-Paños D, Colom-Cadena M, Gomez-Giro G, Muñoz L, Querol-Vilaseca M, Pegueroles J, Rami L, Lladó A, Molinuevo J, Tainta M, Clarimón J, Spires-Jones T, Blesa R, Fortea J, Martínez-Lage P, Sánchez-Valle R, Sabidó E, Bayés À, Belbin O.
Changes in synaptic proteins precede neurodegeneration markers in preclinical Alzheimer’s disease cerebrospinal fluid.
Molecular & Cellular Proteomics. 2019 Jan 3. doi: 10.1074/mcp.RA118.001290.
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[J19] Àngels García-Cazorla, Rafael Artuch and Àlex Bayés
Synaptic Metabolism and Brain Circuitries in inborn errors of metabolism
Journal of Inherited Metabolic Disorders. 2018  Nov 28. doi: 10.1007/s10545-018-00252-y.
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[J18] David Ramos-Vicente, Jie Ji, Ester Gratacòs-Batlle, Gemma Gou, Rita Reig-Viader, Javier Luís, Demian Burguera, Enrique Navas-Pérez, Jordi García-Fernández, Pablo Fuentes-Prior, Hector Escrivá, Nerea Roher, David Soto and Àlex Bayés
Metazoan Evolution of Glutamate Receptors Reveals Unreported Phylogenetic Groups and Divergent Lineage-Specific Events
eLIFE. 2018 Nov 22;7. pii: e35774. doi: 10.7554/eLife.35774.
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[J17] Jie Ji, David Ramos-Vicente, Enrique Navas-Pérez, Carlos Herrera-Úbeda, José Miguel Lizcano,
Jordi Garcia-Fernàndez, Hector Escrivà, Àlex Bayés and Nerea Roher
Characterization of the TLR Family in Branchiostoma lanceolatum and Discovery of a Novel
TLR22-Like Involved in dsRNA Recognition in Amphioxus
Frontiers in Immunology. 2018 Nov 2. doi.org/10.3389/fimmu.2018.02525
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[J16] Àlex Bayés
Setting The Stage For A Role Of The Postsynaptic Proteome In Inherited Neurometabolic Disorders
Journal of Inherited Metabolic Disorders. 2018 Aug 21. doi: 10.1007/s10545-018-0240-x
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[J15] Salgado-Mendialdúa V, Aguirre-Plans J, Guney E, Reig-Viader R, Maldonado R, Bayés À, Oliva B, Ozaita A.
Delta9-tetrahydrocannabinol modulates the proteasome system in the brain.
Biochemical Pharmacology 2018 Nov;157:159-168.
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[J14] Kopanitsa MV, Gou G, Afinowi NO, Bayés À, Grant SGN and Komiyama NH.
Chronic treatment with a MEK inhibitor reverses enhanced excitatory field potentials in Syngap1+/- mice.
Pharmacological Reports 2018 Jun 22;70(4):777-783.
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[J13] Rita Reig-Viader, Carlos Sindreu and Àlex Bayés.
Synaptic proteomics as a means to identify the molecular basis of mental illness: are we getting there?
Progress in Neuropsychopharmacology and Biological Psychiatry 2017 Sep 20. pii: S0278-5846(17)30461-X.
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[J12] Àlex Bayés(^), Mark O Collins, Rita Reig-Viader, Gemma Gou, David Goulding, Abril Izquierdo, Jyoti S. Choudhary, Richard D. Emes and Seth GN Grant(^). (^) Corresponding authors.
Evolution of complexity in the zebrafish synapse proteome.
Nature Communications 2017 Mar 2;8:14613.
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[J11] Diseases of the Synaptic Vesicle: A Potential New Group of Neurometabolic Disorders Affecting Neurotransmission.
Elisenda Cortès-Saladelafont, Alba Tristán-Noguero, Rafael Artuch, Xavier Altafaj, Àlex Bayés, Angels García-Cazorla.
Seminars in Pediatric Neurology 2016 Nov;23(4):306-320.
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[J10] Àlex Bayés, Mark O Collins, Clare M Galtrey, Clémence Simonnet, Marcia Roy, Mike DR Croning, Gemma Gou, Louie N van de Lagemaat, David Milward, Ian R Whittle, Colin Smith, Jyoti S Choudhary and Seth GN Grant.
Human post-mortem synapse proteome integrity screening for proteomic studies of postsynaptic complexes.
Molecular Brain 2014 Nov 28;7:88.
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[J9] Carlos Sindreu, Àlex Bayés, Xavier Altafaj, Jesús Pérez-Clausell.
Zinc Transporter-1 Concentrates at the Post-Synaptic Density of Hippocampal Synapses.
Molecular Brain 2014 Mar 7;7:16.
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[J8] David Soto, Xavier Altafaj, Carlos Sindreu, Àlex Bayés.
Glutamate Receptor Mutations in Psychiatric and Neurodevelopmental Disorders
Communicative and Integrative Biology. 2014, e27887.
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[J7] Àlex Bayés(^) Mark O Collins, Mike DR Croning, Louie N van de Lagemaat, Jyoti S Choudhary and Seth GN Grant(^). (^) Corresponding Authors.
Comparative analysis of human and mouse postsynaptic proteomes identifies high compositional conservation and abundance differences for key synaptic proteins.
PLoS ONE. 2012;7(10):e46683.
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[J6] Kirov G, Pocklington AJ, Holmans P, Ivanov D, Ikeda M, Ruderfer D, Moran J, Chambert K, Toncheva D, Georgieva L, Grozeva D, Fjodorova M, Wollerton R, Rees E, Nikolov I, van de Lagemaat LN, Bayés À, Fernandez E, Olason PI, Böttcher Y, Komiyama NH, Collins MO, Choudhary J, Stefansson K, Stefansson H, Grant SG, Purcell S, Sklar P, O’Donovan MC and Owen MJ.
De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia.
Molecular Psychiatry. 2012 Feb;17(2):142-53.
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[J5] Àlex Bayés & Seth Grant.
Postsynaptic proteins play a major role in neurological and psychiatric diseases.
Advances in Clinical Neurosciences and Rehabilitation 2011 Jul/Aug; 11(3): 13- 14.
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[J4] Àlex Bayés, Louie N van de Laagemat, Mark O. Collins, Mike Croning, Ian R Whittle, Jyoti Choudhary and Seth GN Grant.
Characterisation of the proteome, disease and evolution of the human postsynaptic density.
Nature Neuroscience 2011 Jan; 14(1): 19-21.
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[J3] Ilse Delint-Ramirez, Esperanza Fernandez, Àlex Bayés, Emese Kicsi, Noboru H Komiyama, and Seth GN Grant.
In Vivo Composition of NMDA Receptor Signalling Complexes Differs between Membrane Subdomains and Is Modulated by PSD-95 And PSD-93.
Journal of Neuroscience 2010 Jun 16, 30(24):8162– 8170.
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[J2] Àlex Bayés and Seth G.N. Grant
Neuroproteomics: understanding the organization and complexity of the brain proteome.
Nature Reviews in Neuroscience 2009 Sep; 10(9):635-46.
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[J1] Richard D. Emes*, Andrew J. Pocklington*, Christopher N.G. Anderson*, Àlex Bayés, Mark O. Collins, Catherine A. Vickers, Mike D.R. Croning, Bilal R. Malik, Jyoti S. Choudhary, J. Douglas Armstrong, Seth G.N. Grant. (*) These authors equally contributed to the work.
Evolutionary expansion and anatomical specialization of synapse proteome complexity.
Nature Neuroscience 2008 Jul;11(7): 799-806.
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Book Chapters:

[BC2] Rita Reig-Viader and Àlex Bayés. Quantitative In-Depth profiling of the Postsynaptic Density Proteome to Understand the Molecular Mechanisms Governing Synaptic Physiology and Pathology. Neuromethods. Current Proteomic Approaches Applied to Brain Function. 2017 Human Press, Springer Protocols. ISBN 978-1-4939-7119-0.
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[BC1] Bayés À and Grant SGN. Synapse Proteomes and Disease: The MASC Paradigm. In: Sala C, Verpelli C, editors. Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability; 2016. p. 85–99.
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Books:

[B1] Rita Reig-Viader and Àlex Bayés. La Neurogenómica. La genética del cerebro (in Spanish).
2017, Edited by National Geographic in partnership with RBA Coleccionables.
Part of the collection ‘Los Desafios de la Ciencia’.
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